Article

Focal adhesion prevention on nanoparticle substrates upregulates stemness gene expression in primary melanocytes

2025-12-29

Abstract excerpt

<h4>Hypothesis</h4> Cell focal adhesions are initiated by interactions of cell surface integrins with extracellular matrix (ECM) proteins, and cells which lack focal adhesions have been associated with an intermediate adhesive state, which is more labile towards cell reprogramming. We hypothesized that cells cultured under conditions where they exhibit reduced focal adhesions will assume an intermediate adhesive...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 52d9ddc3-2d78-5c94-b459-717cfcbcf2b0
DOI: 10.64898/2025.12.28.693089

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Focal adhesion prevention on nanoparticle substrates upregulates stemness gene expression in primary melanocytesDOI 10.64898/2025.12.28.693089Read

Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency.Semantic proximity Read

MITF reprograms the extracellular matrix and focal adhesion in melanomaSemantic proximity Read

A Modular Bioinstructive Platform for Additive-Free, Topography-Driven Stem Cell Differentiation and PatterningSemantic proximity Read

Selective Photomechanical Detachment and Retrieval of Divided Sister Cells from Enclosed Microfluidics for Downstream AnalysesSemantic proximity Read

Strategies to enhance epithelial–mesenchymal interactions for human hair follicle bioengineeringSemantic proximity Read

ZO-1 remodels the cytoskeleton and boosts self-renewal in OCT4-reprogrammed human hair follicle mesenchymal stem cells through adherens junction pathwaySemantic proximity Read

Engineering cellular microenvironments to improve cell-based drug testing.Semantic proximity Read

The Effect of Micro- and Nanoscale Surface Topographies on Silk on Human Corneal Limbal Epithelial Cell DifferentiationSemantic proximity Read

A photoactivatable nanopatterned substrate for analyzing collective cell migration with precisely tuned cell-extracellular matrix ligand interactions.Semantic proximity Read

Injury-Free In Vivo Delivery and Engraftment into the Cornea Endothelium Using Extracellular Matrix Shrink-Wrapped CellsSemantic proximity Read

Superresolution architecture of pluripotency guarding adhesionsSemantic proximity Read

Arp2/3 mediated dynamic lamellipodia of the hPSC colony edges promote liposome-based DNA deliverySemantic proximity Read