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Article

Engineering cellular microenvironments to improve cell-based drug testing.

Drug discovery today - 1 Jun 2002

Bhadriraju Kiran, Chen Christopher S

Abstract excerpt

Recent progress in the biology of cell adhesion is enabling cell culture models to better reproduce in vivo functions. Cues from adhesion to extracellular matrix and neighboring cells are important regulators of cell behaviors. The recent adaptation of semiconductor tools to spatially organize cells and their adhesions has enhanced our ability to engineer cell functions ex vivo. By using these tools to create...

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Identifiers

PMID: 12047872
DOI: 10.1016/s1359-6446(02)02273-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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