Article

ZO-1 remodels the cytoskeleton and boosts self-renewal in OCT4-reprogrammed human hair follicle mesenchymal stem cells through adherens junction pathway

2024-02-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The challenge of expanding haematopoietic stem/progenitor cells (HSPCs) in vitro has limited the clinical application of this technology. Human hair follicle mesenchymal stem cells (hHFMSCs) can be reprogrammed to generate intermediate stem cells by introducing only OCT4 (hHFMSCs<sup>OCT4</sup>). Prestimulating these cells with a low concentration of the cytokin...

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Literature Corpus work: 0be3fa4f-f88d-5631-b3e2-124d14f82df9
DOI: 10.21203/rs.3.rs-3944642/v1

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