Article

Structural impairments of the heart associating with ETB mutation, a cause of Hirschsprung disease

2020-07-15

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>HSCR, a colonic neurocristopathy affecting 1/5000 births, was suggested to associate with cardiac septal defects and conotruncal malformations. However, we question subtle cardiac changes maybe more commonly present due to multi-regulations by HSCR candidate genes, in this instance, ET<sub>B</sub>. To investigate, we compared the cardiac morphology and quantitati...

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Literature Corpus work: 52b40515-6f40-5f20-8780-36a05d6ef632
DOI: 10.21203/rs.3.rs-34298/v1

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