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Embryonic alcohol exposure in zebrafish predisposes adults to cardiomyopathy and diastolic dysfunction

18 Jun 2024

Abstract excerpt

AIMS: Fetal alcohol spectrum disorders (FASDs) impact up to 0.8% of the global population. However, cardiovascular health outcomes in adult patients, along with predictive biomarkers for cardiac risk stratification, remain unknown. Our aim was to utilize a longitudinal cohort study in an animal model to evaluate the impact of embryonic alcohol exposure (EAE) on cardiac structure, function, and transcriptional...

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PMID: 38900908
DOI: 10.1093/cvr/cvae139

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