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Article

Structural heart defects associated with ETB mutation, a cause of Hirschsprung disease.

BMC cardiovascular disorders - 2 Oct 2021

Chen Ko-Chin, Chen Ko-Chien, Song Zan-Min, Croaker Geoffrey D

Abstract excerpt

BACKGROUND: HSCR, a colonic neurocristopathy affecting 1/5000 births, is suggested to associate with cardiac septal defects and conotruncal malformations. However, we question subtle cardiac changes maybe more commonly present due to multi-regulations by HSCR candidate genes, in this instance, ETB. To investigate, we compared the cardiac morphology and quantitative measurements of sl/sl rat to those of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34600481
DOI: 10.1186/s12872-021-02281-2
PMCID: PMC8487587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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