Physical exercise may exert its therapeutic influence on Alzheimer's disease through the reversal of mitochondrial dysfunction via SIRT1–FOXO1/3–PINK1–Parkin-mediated mitophagy

Abstract excerpt

• Physical exercise efficiently prevents the progression of Alzheimer's disease and mitigates the risk of developing the disease. • Physical exercise acts against the development and progression of Alzheimer's disease via promoting mitochondrial fitness. • Physical exercise may exert its therapeutic influence on Alzheimer's disease through the reversal of mitochondrial dysfunction via...

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