Article

Promising Modulatory Effects of Autophagy on APP Processing as a Potential Treatment for Alzheimer's Disease

2020-10-09

Abstract excerpt

Autophagy refers to the degradation of cytoplasmic constituents by a lysosomal-mediated pathway, which plays a critical role in maintaining cellular homeostasis. Importantly, dysregulation of autophagy has been implicated in multiple neurodegenerative disorders. Previous studies reported that autophagy affects the processing of amyloid precursor protein (APP), thus stimulating β‐amyloid (Aβ) production i...

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Literature Corpus work: 525d9732-ec18-53ed-b8ee-bfecca4935a4
DOI: 10.20944/preprints202010.0195.v1

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