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Autophagy in alzheimer disease pathogenesis and its therapeutic values

8 May 2025

Abstract excerpt

Alzheimer disease (AD) is the most common form of dementia with hallmarks of β-amyloid deposits, neurofilament tangles, synaptic loss and neuronal death in the patient's brain. AD is a heavy burden in an ageing society as there are no effective therapies in treating the causes or slowing down its progression. Autophagy is a conserved process through formation of double membrane structure, namely autophagosome...

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PMID: 40395993
DOI: 10.1080/27694127.2025.2471677

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