Article

Epigenetic silencing and tumor suppressor gene of HAND2 by targeting ERK signaling in colorectal cancer

2021-10-18

Abstract excerpt

<title>Abstract</title> <p>Background The screening biomarkers for early detection of colorectal cancer (CRC) is lacking. The aim is to identify epigenetic silenced genes and clarify its roles and underlying mechanism in CRC. We conducted integrative analyses of epigenome-wide Human Methylation 450K arrays and transcriptome to screen out candidate epigenetic driver genes with transcription silencing. Methylated...

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Literature Corpus work: 52576d4a-02ce-5f62-8b12-245ae263c1c8
DOI: 10.21203/rs.3.rs-945202/v1

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