Single-cell RNA sequencing of chronic idiopathic erythroderma defines disease-specific markers

Abstract excerpt

Background Chronic erythroderma is a potentially life-threatening condition that can be caused by various diseases, but approximately 30% of cases remain idiopathic, often with insufficient treatment options. Objective We sought to establish a molecular disease map of chronic idiopathic erythroderma (CIE). Methods We performed single-cell RNA sequencing combined with T-cell receptor sequencing of blood and skin...

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