Article

APOBEC3A drives acquired resistance to targeted therapies in non-small cell lung cancer

2021-01-21

Abstract excerpt

Acquired drug resistance to even the most effective anti-cancer targeted therapies remains an unsolved clinical problem. Although many drivers of acquired drug resistance have been identified 1‒6 , the underlying molecular mechanisms shaping tumor evolution during treatment are incompletely understood. The extent to which therapy actively drives tumor evolution by promoting mutagenic processes 7 or simply provid...

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Literature Corpus work: 524541cf-0e04-5f79-9178-76c4cffa3d33
DOI: 10.1101/2021.01.20.426852

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