Article

Impact of YAQ001 on the gut microbiome, permeability and markers of systemic inflammation in patients with cirrhosis

2025-12-09

Abstract excerpt

<h4>Background and aims</h4> YAQ001 is a novel, highly engineered, non-absorbable, gut-restricted, multiporous, carbon bead adsorbent. Pre-clinical studies and a clinical trial confirmed its therapeutic potential and safety in patients with cirrhosis. The aims of this sub study were to evaluate the effect of YAQ001 on the gut microbiome and its association with biomarkers of gut permeability and systemic inflamma...

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Literature Corpus work: 5227af47-efb3-5c12-8373-56a67e4ef281
DOI: 10.64898/2025.12.01.25341286

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