Article

Impact of Yaq-001, a non-absorbable, engineered carbon bead of controlled porosity in rodent models of cirrhosis and acute on chronic liver failure

2023-08-17

Abstract excerpt

<h4>Objective</h4> Translocation of gut bacterial lipopolysaccharide (LPS) is associated with complications of cirrhosis. Current strategies to target bacterial translocation are limited to antibiotics with risk of resistance. This study aims to explore therapeutic potential of a non-absorbable, engineered carbon bead, Yaq-001 in cirrhosis and acute-on-chronic liver failure (ACLF) models. <h4>Design</h4> The per...

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Literature Corpus work: 470ae958-a8d0-5e8c-a7c9-fcd8564eee7c
DOI: 10.1101/2023.08.15.553396

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