Article

Loss of SORCS2 is associated with neuronal DNA double-strand breaks

2021-04-29

Abstract excerpt

SORCS2 is one of five proteins that constitute the Vps10p-domain receptor family. Members of this family play important roles in cellular processes linked to neuronal survival, differentiation and function. Genetic and functional studies implicate SORCS2 in cognitive function, as well as in neurodegenerative and psychiatric disorders. DNA damage and DNA repair deficits are linked to ageing and neurodegeneration, a...

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Literature Corpus work: 51fa571a-8896-530c-b173-064137a404e6
DOI: 10.1101/2021.04.28.441600

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