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Article

DNA single-strand break repair and spinocerebellar ataxia with axonal neuropathy-1.

Neuroscience - 14 Apr 2007

el-Khamisy S F, Caldecott K W

Abstract excerpt

DNA single-strand breaks (SSBs) are the commonest DNA lesions arising spontaneously in cells, and if not repaired may block transcription or may be converted into potentially lethal/clastogenic DNA double-strand breaks (DSBs). Recently, evidence has emerged that defects in the rapid repair of SSB...

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Source

Identifiers

PMID: 17045754
DOI: 10.1016/j.neuroscience.2006.08.048

Genes

TDP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17045754-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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