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Finding memo: versatile interactions of the VPS10p-Domain receptors in Alzheimer’s disease

18 Nov 2022

Abstract excerpt

The family of VPS10p-Domain (D) receptors comprises five members named SorLA, Sortilin, SorCS1, SorCS2 and SorCS3. While their physiological roles remain incompletely resolved, they have been recognized for their signaling engagements and trafficking abilities, navigating a number of molecules between endosome, Golgi compartments, and the cell surface. Strikingly, recent studies connected all the VPS10p-D...

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PMID: 36397124
DOI: 10.1186/s13024-022-00576-2

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