Article

Microscale spatial fragmentation promotes bacterial survival under antibiotics

2026-03-18

Abstract excerpt

Most bacteria inhabit fragmented microscale environments rather than well-mixed systems in which antibiotic efficacy is typically defined. Here, we show that microscale spatial fragmentation alone can deterministically promote bacterial survival under antibiotic exposure. A coarse-grained theoretical model predicts that, at fixed bulk cell density and antibiotic concentration, fragmentation generates refuges throu...

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Literature Corpus work: 51d49acf-5883-5070-8a8f-2492d7788091
DOI: 10.64898/2026.03.17.712417

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