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Article

Distinct single-cell morphological dynamics under beta-lactam antibiotics.

Molecular cell - 14 Dec 2012

Yao Zhizhong, Kahne Daniel, Kishony Roy

Abstract excerpt

The bacterial cell wall is conserved in prokaryotes, stabilizing cells against osmotic stress. Beta-lactams inhibit cell-wall synthesis and induce lysis through a bulge-mediated mechanism; however, little is known about the formation dynamics and stability of these bulges. To capture processes of different timescales, we developed an imaging platform combining automated image analysis with live-cell microscopy at...

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Identifiers

PMID: 23103254
DOI: 10.1016/j.molcel.2012.09.016
PMCID: PMC3525771

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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