Article

ARID3a-Expressing Naïve B Cells in SLE have an Activated Phenotype and Transiently Express Surface CD68

2026-07-16

Abstract excerpt

Numbers of ARID3a ( AT - R ich Interaction D omain 3a ) -expressing B lymphocytes from patients with systemic lupus erythematosus (SLE) are associated with increased disease activity. Normally, ARID3a-expressing circulating naïve B cells are rare, but in SLE naïve B cells dramatically increase ARID3a expression. We found that in vitro stimulation of B lymphocytes from healthy individuals with a cocktail of cy...

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Literature Corpus work: 51b22e8b-e187-5cdd-b0f3-df54c26b3a01
DOI: 10.64898/2026.07.10.737835

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