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Identification of alterations in macrophage activation associated with disease activity in systemic lupus erythematosus

18 Dec 2018

Abstract excerpt

Systemic lupus erythematosus (SLE) is characterized by abnormalities in B cell and T cell function, but the role of disturbances in the activation status of macrophages (Mϕ) has not been well described in human patients. To address this, gene expression profiles from isolated lymphoid and myeloid populations were analyzed to identify differentially expressed (DE) genes between healthy controls and patients with...

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PMID: 30562343
DOI: 10.1371/journal.pone.0208132

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