Article

Activation of NLRP3 Inflammasome by Virus-like Particles of Human Polyomaviruses in Macrophages

2021-11-16

Abstract excerpt

Viral antigens can activate phagocytes inducing inflammation but the mechanisms are barely explored. This study aimed to investigate the capability of viral oligomeric proteins of different structure to induce inflammatory response in macrophages. Human THP-1 cell line was used to prepare macrophages which were treated with filamentous nucleocapsid-like particles (NLPs) of paramyxoviruses and spherical virus-like...

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Literature Corpus work: 517dbf06-fa69-5950-9045-bb51f4e3b279
DOI: 10.1101/2021.11.15.468577

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