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Article

The multifaceted roles of NLRP3-modulating proteins in virus infection

30 Aug 2022

Abstract excerpt

The innate immune response to viruses is critical for the correct establishment of protective adaptive immunity. Amongst the many pathways involved, the NLRP3 [nucleotide-binding oligomerisation domain (NOD)-like receptor protein 3 (NLRP3)] inflammasome has received considerable attention, particularly in the context of immunity and pathogenesis during infection with influenza A (IAV) and SARS-CoV-2, the...

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PMID: 36110852
DOI: 10.3389/fimmu.2022.987453

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