Article

Sequential development of embryoblast-like memory entities in human cancer tissues: An evolutionary self-repair structure with pluripotentiality

2020-10-04

Abstract excerpt

Hidden collective organization of cancer cells can partially or completely return to embryoid genotype-phenotype with the plasticity to transform their morphology on cell embryoblast-like memory entities by expression of dormant genes that arise from embryogenesis. After hundreds of driver mutations, cancer cells gain new abilities or attributes and recapitulate early stages of embryogenesis. Our findings document...

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Literature Corpus work: 517b56be-4cff-566d-9809-1ecb83ada12b
DOI: 10.1101/2020.10.02.324376

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