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Article

Cancer attractors: a systems view of tumors from a gene network dynamics and developmental perspective.

Seminars in cell & developmental biology - 1 Sept 2009

Huang Sui, Ernberg Ingemar, Kauffman Stuart

Abstract excerpt

Cell lineage commitment and differentiation are governed by a complex gene regulatory network. Disruption of these processes by inappropriate regulatory signals and by mutational rewiring of the network can lead to tumorigenesis. Cancer cells often exhibit immature or embryonic traits and dysregulated developmental genes can act as oncogenes. However, the prevailing paradigm of somatic evolution and multi-step...

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Identifiers

PMID: 19595782
DOI: 10.1016/j.semcdb.2009.07.003
PMCID: PMC2754594

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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