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Drug screening model meets cancer organoid technology

17 Aug 2020

Abstract excerpt

Tumor organoids inherit the genomic and molecular characteristics of the donor tumor, which not only bridge the gap between genome and phenotype but also circumvent the disadvantages such as genetic information change by using 2D cell lines and the mouse-specific tumor evolution in patient-derived xenograft (PDX). So, cancer organoid has been widely applied to preclinical drug evaluation, biomarker...

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PMID: 32822897
DOI: 10.1016/j.tranon.2020.100840

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