Back to search

Article

PPP3CB inhibits pancreatic cancer progression via promoting translocation of ATOH8 and further transcriptionally regulating Sp1

2024-04-30

Abstract excerpt

<title>Abstract</title> <p>Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy which lacks effective therapeutic targets. We previously demonstrated that low expression level of PPP3CB was correlated with poor prognosis in PDAC but its function and mechanism remain to be elucidated. Here, we found that the expression of PPP3CB was higher in PDAC patients with early stage than that in late stage....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
be2d9d11-dbdf-5c2b-bca5-3d22358ed44b
DOI
10.21203/rs.3.rs-4123518/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
PPP3CB inhibits pancreatic cancer progression via promoting translocation of ATOH8 and further transcriptionally regulating Sp1DOI 10.21203/rs.3.rs-4123518/v1
SHCBP1 interacting with EOGT enhanced O-GlcNAcylation of NOTCH1 and promoted the development of pancreatic cancer .Semantic proximity
Comprehensive Genomic Analysis of the Prognostic and Immunological Characteristics of Tertiary Lymphoid structures and CD8+ T-cells in Pancreatic Ductal AdenocarcinomaSemantic proximity
PAFAH1B3 is a KLF9 target gene and promotes proliferation and metastasis in pancreatic cancerSemantic proximity
The protein phosphatase-2A subunit PR130 is linked to cytotoxic protein aggregate formation in mesenchymal pancreatic ductal adenocarcinoma cellsSemantic proximity
Identification of new biomarkers for pancreatic cancer management: A bioinformatics analysisSemantic proximity
A Pan-cancer Analysis of the Prognostic and Immunological Role of PPP1R14ASemantic proximity
Clinical Significance and Prognostic Value of the Expression of Fibronectin Type III Domain Containing 3B in Pancreatic CarcinomaSemantic proximity
High expression of the LAMA3/AC245041.2 gene pair associated with KRAS mutation and poor survival in pancreatic adenocarcinoma: A comprehensive TCGA analysisSemantic proximity
The ITGA6-AEBP2 Complex Promotes Transcriptional Activation of GSK3β to Augment Wntβ-Catenin Signaling and Stemness in Pancreatic CancerSemantic proximity
Pan-cancer analysis of ARMCX genes identifies ARMCX1 as a novel suppressor gene for pancreatic carcinomaSemantic proximity
The role of phosphoprotein phosphatases catalytic subunit genes in pancreatic cancerSemantic proximity
Prognosis and personalized treatment prediction of IGF2BP2- mediated m6A modification patterns in pancreatic cancerSemantic proximity
Select a neighboring publication to make it the new centre.