Article

The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells

2023-11-15

Abstract excerpt

As a major source of cellular serine and threonine phosphatase activity, protein phosphatase-2A (PP2A) modulates signaling pathways in health and disease. PP2A complexes consist of catalytic, scaffolding, and B-type subunits. Seventeen protein phosphatase-2A (PP2A) B-type subunits direct PP2A complexes to selected substrates. It is ill-defined how PP2A B-type subunits determine the growth and drug responsiveness o...

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Literature Corpus work: 533052ee-a476-5f80-ad1f-00d9eac355b0
DOI: 10.21203/rs.3.rs-3597331/v1

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