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Article

Identification of Genes Required for Long-Term Survival of Legionella pneumophila in Water.

mSphere - 20 Apr 2023

Aurass Philipp, Kim Seongok, Pinedo Victor, Cava Felipe, Isberg Ralph R

Abstract excerpt

Long-term survival of Legionella pneumophila in aquatic environments is thought to be important for facilitating epidemic outbreaks. Eliminating bacterial colonization in plumbing systems is the primary strategy that depletes this reservoir and prevents disease. To uncover L. pneumophila determinants facilitating survival in water, a Tn-seq strategy was used to identify survival-defective mutants during 50-day...

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Identifiers

PMID: 36988466
DOI: 10.1128/msphere.00454-22
PMCID: PMC10117105

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