Article

Ohno-miRNAs: intragenic miRNA pairs derived from whole-genome duplication

2025-01-18

Abstract excerpt

<h4>ABSTRACT</h4> Two rounds of whole-genome duplication (WGD) occurred about 500 million years ago and played a major role in the evolution of the vertebrate genomes. Human genes derived from WGD are called “ohnologs”. Ohnologs are involved in fundamental biological processes and significantly contributed to the complexity of the human gene regulatory network. Given the central role of miRNAs in gene regulation,...

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Literature Corpus work: 50e1e4af-3d8f-5a75-b395-7fedc7a1d744
DOI: 10.1101/2025.01.16.632905

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