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Reduction of clonal hematopoiesis mutation burden in coronary patients treated with low-dose colchicine

2024-10-18

Abstract excerpt

<h4>ABSTRACT</h4> Clonal hematopoiesis involves mutations in hematopoietic stem/progenitor cells, which increase the risk of cardiovascular disease, particularly under pro-inflammatory conditions. This study assessed the impact of the anti-inflammatory medication colchicine on clonal hematopoiesis in patients with recent myocardial infarction from the COLCOT trial. Participants were randomly assigned to low-dose...

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Literature Corpus work
50de41b8-8e4b-5922-a756-5c5bed6b8451
DOI
10.1101/2024.10.17.24315679
Open publication

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Reduction of clonal hematopoiesis mutation burden in coronary patients treated with low-dose colchicineDOI 10.1101/2024.10.17.24315679
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