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Article

Prognostic significance of clonal hematopoiesis in STEMI: a 10-year follow-up reveals high-risk gene mutations.

Human genomics - 12 May 2025

Fan Wen-Lang, Yeh Jih-Kai, Hsieh Li-Ching, Tsai Ming-Lung, Ho Ming-Yun, Huang Yi-Chun, Hsieh I-Chang, Wen Ming-Shien, Wang Chao-Yung

Abstract excerpt

BACKGROUND: To elucidate the extent and clinical implications of clonal hematopoiesis of indeterminate potential (CHIP) prevalence in patients with ST-segment elevation myocardial infarction (STEMI), and to evaluate its utility as a contributory factor for risk stratification in long-term outcomes. METHODS: Whole-exome sequencing was performed in a cohort of 101 patients presenting with STEMI who underwent...

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Identifiers

PMID: 40355940
DOI: 10.1186/s40246-025-00757-2
PMCID: PMC12067743

Genes

ASXL1
CREBBP

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