Article

“Loss of alkyladenine DNA glycosylase alters gene expression in the developing mouse brain and leads to reduced anxiety and improved memory”

2023-10-05

Abstract excerpt

<h4>ABSTRACT</h4> Neurodevelopment is a tightly coordinated process, during which the genome is exposed to spectra of endogenous agents at different stages of differentiation. Emerging evidence indicates that DNA damage is an important feature of developing brain, tightly linked to gene expression and neuronal activity. Some of the most frequent DNA damage includes changes to DNA bases, which are recognized by DN...

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Literature Corpus work: 50c8080f-541a-5266-8ae1-1e23c03f37fc
DOI: 10.1101/2023.10.05.561113

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