Article
Relevance of the viral Spike protein/cellular Estrogen Receptor-α interaction for endothelial-based coagulopathy induced by SARS-CoV-2
2022-10-04
Abstract excerpt
Severe coagulopathy has been observed at the level of the microcirculation in several organs including lungs, heart and kidneys in patients with COVID-19, and in a minority of subjects receiving the SARS-CoV-2 vaccine. Various mechanisms have been implicated in these effects, including increases in circulating neutrophil extracellular traps, excessive inflammation, and endothelial dysfunction. Even if a correlatio...
Topics
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- Adipokines, Inflammation, and Metabolic Diseases
- COVID-19 Clinical Research Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Inflammasome and immune disorders
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Phagocytosis and Immune Regulation
- Platelet Disorders and Treatments
- SARS-CoV-2 and COVID-19 Research
Identifiers and source
- Literature Corpus work
- 50a716f6-bd45-513c-a418-1885bad2a02c
- DOI
- 10.1101/2022.10.04.510657
