Article

SOX9 regulation of Hexokinase 1 controls neuroinflammatory astrocyte subtypes in neuropathic pain

2025-02-19

Abstract excerpt

<title>Abstract</title> <p>Neuropathic pain (NeP) results from nerve damage or disease, lacking effective treatments. Astrocytes contribute to long-lasting neuroinflammation in the dorsal horn, driving NeP development. Directly targeting astrocytes is not feasible due to their roles in supporting neuronal homeostasis and pain resolution. Despite this understanding, the heterogeneity of astrocytes and the regulati...

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Literature Corpus work: 5077a7e7-6a59-58e8-b359-8205d50163c8
DOI: 10.21203/rs.3.rs-5916660/v1

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