Article

Colocalization and discordance between plasma and brain protein quantitative trait loci

2026-05-05

Abstract excerpt

Studies of protein quantitative trait loci (pQTLs) provide opportunities to interpret complex trait genetics and identify potential biomarkers and therapeutic targets. Circulating proteins are commonly used in pQTL studies due to the accessibility of blood-based measurements, but their levels may not always reflect regulation in disease-relevant tissues. We assessed colocalization and discordance between plasma an...

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Literature Corpus work: 5055a1b1-6a15-593b-b3fd-db3b738dd93a
DOI: 10.64898/2026.05.01.722237

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