Article

Effect of Heparanase Inhibitor on Tissue Factor Overexpression in Platelets and Endothelial Cells Induced by Anti-β2-GPI Antibodies

2020-11-02

Abstract excerpt

Anti-phospholipid syndrome (APS) is characterized by arterial and/or venous thrombosis and pregnancy morbidity associated with the presence of “anti-phospholipid antibodies”. Thrombosis may be the result of a hypercoagulable state related to activation of endothelial cells and platelets by anti-2-glycoprotein I (β2-GPI) antibodies. Anti-β2-GPI antibodies induce a proinflammatory and procoagu...

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Literature Corpus work: 4ff4a00b-abfb-5b59-bdc4-9e209a1d953c
DOI: 10.20944/preprints202011.0008.v1

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