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Antiphospholipid antibodies induce proinflammatory and procoagulant pathways in endothelial cells

1 Jan 2023

Abstract excerpt

Antiphospholipid syndrome (APS) is an autoimmune thrombophilia characterized by recurrent thrombotic events and/or pregnancy morbidity in the presence of antiphospholipid antibodies detected either as anti-cardiolipin, anti-β2 Glycoprotein I (anti-β2GPI) or Lupus anticoagulant (LA). Endothelial deregulation characterizes the syndrome. To address gene expression changes accompanying the development of autoimmune...

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PMID: 37216142
DOI: 10.1016/j.jtauto.2023.100202

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