Article

Quantification of double stranded DNA breaks and telomere length as proxies for corneal damage and replicative stress in 64 human keratoconus corneas

2018-01-08

Abstract excerpt

<h4>Purpose</h4> The pathogenesis of keratoconus (KC) is multifactorial and associated with oxidative stress and subsequent DNA damage. The aim of this study was to investigate differences in DNA damage and replicative stress in patients with KC, and in both healthy and diseased controls. <h4>Methods</h4> Sixty-four corneal buttons were obtained from 27 patients with KC after corneal transplant surgery, 21 patie...

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Literature Corpus work: 4fbd7076-70ae-5200-a792-147ece5efe80
DOI: 10.1101/244871

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