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Article

Epigenetic mechanisms might help explain environmental contributions to the pathogenesis of keratoconus.

Eye & contact lens - 1 Nov 2014

McMonnies Charles W

Abstract excerpt

The etiology of keratoconus (KC) seems to involve genetic and/or environmental factors such as rubbing and/or contact lens trauma and/or exposure to ultraviolet radiation. An examination of the possibility that epigenetic mechanisms could contribute to the tissue changes in KC has been considered in this review. The tissue changes in KC result in thinning and/or other forms of mechanical weakening of the cornea,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25320960
DOI: 10.1097/ICL.0000000000000078

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