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Article

Phenotypic Alterations of CD8+ and CD8- CD56+ NK Cell Subsets in Moderate and Severe COVID-19 Disease.

Journal of immunology research - 1 Jan 2026

Meggyes Matyas, Nagy David U, Toth Ildiko, Mezosi Livia, Sipos David, Peterfalvi Agnes, Szereday Laszlo

Abstract excerpt

The COVID-19 pandemic has created a global health challenge. Severe cases are associated with immune system dysfunction, which can lead to uncontrolled inflammation. There are no published data on the specific roles of natural killer (NK)-cell subsets and immune checkpoint (IC) molecules in disease severity. Thirty-five patients diagnosed with COVID-19 and 14 healthy controls were involved in the study. From...

Read the complete abstract on PubMed

Topics

Humans
COVID-19
Killer Cells, Natural
Female
Male
CD56 Antigen
Middle Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

SARS-CoV-2

Aged

Adult

CD8-Positive T-Lymphocytes

Severity of Illness Index

Receptors, Immunologic

Antigens, CD

Antigens, Differentiation, T-Lymphocyte

T Lineage-Specific Activation Antigen 1

Programmed Cell Death 1 Receptor

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 42730601
DOI: 10.1155/jimr/8647361
PMCID: PMC13570445

Genes

CD226
CD69
TIGIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

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