Article

PIK3CA mutations associated with a poor postoperative prognosis in patients with pulmonary pleomorphic carcinoma: A retrospective cohort study

2022-08-03

Abstract excerpt

<h4>Background: </h4> Pulmonary pleomorphic carcinoma (PPC) is a rare type of non-small cell lung cancer characterized by high malignancy and a poor prognosis. PPC is associated with a high frequency of postoperative relapse, and shows resistance to chemotherapy. The high malignancy of cancers is associated with genomic instability, which is related to mutations of tumor suppressor genes, such as tumor protein p53...

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Literature Corpus work: 4fb1be13-cb71-57cb-9eb5-c3898d0f76ce
DOI: 10.21203/rs.3.rs-1813803/v1

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