Article
Molecular profiles of EGFR, K-ras, c-met, and FGFR in pulmonary pleomorphic carcinoma, a rare lung malignancy.
Journal of cancer research and clinical oncology - 1 Aug 2011
Lee Soohyeon, Kim Youngwook, Sun Jong-Mu, Choi Yoon La, Kim Jhin Gook, Shim Young-Mog, Park Yeon Hee, Ahn Jin Seok, Park Keunchil, Han Jung Ho, Ahn Myung-Ju
Abstract excerpt
BACKGROUND: Pulmonary pleomorphic carcinoma (PPC) is a rare type of lung cancer characterized by the poor response to conventional chemotherapy and subsequent disappointing outcomes. Therefore, it is paramount to delineate the molecular characteristics of this disease entity. METHODS: In this study, we retrospectively examined the surgical specimens of 61 patients who underwent lung surgery. Mutational or gene...
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