Article
PIK3CA mutations as prognostic factor in squamous cell lung carcinoma.
Lung cancer (Amsterdam, Netherlands) - 1 Jan 2017
McGowan Marc, Hoven Aleksandra Silye, Lund-Iversen Marius, Solberg Steinar, Helland Åslaug, Hirsch Fred R, Brustugun Odd Terje
Abstract excerpt
OBJECTIVES: Mutation in the PIK3CA gene is reported frequent in squamous cell carcinomas of the lung, but its potential prognostic role is still obscure. We have studied the prognostic importance of PIK3CA mutations as well as the relation to other markers in a large number of early stage lung cancers of squamous carcinoma subtype. PATIENTS AND METHODS: Tumour tissue was obtained from 308 consecutively operated...
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