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Comprehensive molecular profiling of pulmonary pleomorphic carcinoma

22 Jun 2021

Abstract excerpt

Information regarding the molecular features of pulmonary pleomorphic carcinoma (PPC) is insufficient. Here, we performed next-generation sequencing to determine the genomic and transcriptomic profiles of PPC. We sequenced the DNAs and RNAs of 78 specimens from 52 patients with PPC. We analyzed 15 PPC cases to identify intratumoral differences in gene alterations, tumor mutation burden (TMB), RNA expression, and...

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PMID: 34158601
DOI: 10.1038/s41698-021-00201-3

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