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Multi-Omics Unveils Strain-Specific Neuroactive Metabolite Production Linked to Inflammation Modulation by <i>Bacteroides</i> and Their Extracellular Vesicles

2024-08-20

Abstract excerpt

Bacteroides species are key members of the human gut microbiome and play crucial roles in gut ecology, metabolism, and host-microbe interactions. This study investigated the strain-specific production of neuroactive metabolites by 18 Bacteroidetes (12 Bacteroides , 4 Phocaeicola , and 2 Parabacteroides ) using multi-omics approaches. Genomic analysis revealed a significant potential for producing GABA, tryptoph...

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Literature Corpus work
4f768cef-7b6c-52a0-9dc2-8dfd0a9caada
DOI
10.1101/2024.08.19.608651
Open publication

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Multi-Omics Unveils Strain-Specific Neuroactive Metabolite Production Linked to Inflammation Modulation by <i>Bacteroides</i> and Their Extracellular VesiclesDOI 10.1101/2024.08.19.608651
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