Article

Sialic acid-binding immunoglobulin-like lectin-6 (SIGLEC6) is increased by hypoxia and inflammation; relevance to preeclampsia

2025-08-14

Abstract excerpt

<title>Abstract</title> <p>SIGLEC6, a human-specific transmembrane receptor, is highly expressed in placenta. Our team have identified elevated SIGLEC6 in maternal circulation preceding preeclampsia and in women with preeclampsia, correlating with disease severity. This study aimed to characterise SIGLEC6 relevant to preeclampsia using human (cyto)trophoblast stem cells (hTSCs) and primary Human Umbilical Vein En...

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Literature Corpus work: 4f5bfe11-df6c-5b4c-81c0-cf6bf6f83ba1
DOI: 10.21203/rs.3.rs-7164266/v1

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