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Article

HTRA1 in Placental Cell Models: A Possible Role in Preeclampsia

1 May 2023

Abstract excerpt

The HtrA serine peptidase 1 (HTRA1) is a multidomain secretory protein with serine–protease activity involved in the regulation of many cellular processes in both physiological and pathological conditions. HTRA1 is normally expressed in the human placenta, and its expression is higher in the first trimester compared to the third trimester, suggesting an important role of this serine protease in the early phases...

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PMID: 37232715
DOI: 10.3390/cimb45050246

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