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<i>Plasmodium falciparum</i> Acetyl-CoA Synthetase is essential for parasite intraerythrocytic development and chromatin modification

2021-06-13

Abstract excerpt

The malaria parasite Plasmodium falciparum possesses a unique Acetyl-CoA Synthetase (PfACS) which provides acetyl moieties for different metabolic and regulatory cellular pathways. We characterized PfACS and studied its role focusing on epigenetic modifications using the var gene family as reporter genes. For this, mutant lines to modulate plasmodial ACS expression by degron-mediated protein degradation or riboz...

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Literature Corpus work
4f307786-d365-56d5-a1b0-aa46cb22437f
DOI
10.1101/2021.06.13.448207
Open publication

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<i>Plasmodium falciparum</i> Acetyl-CoA Synthetase is essential for parasite intraerythrocytic development and chromatin modificationDOI 10.1101/2021.06.13.448207
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