Article

Cross-reactive human antibody responses to H5N1 influenza virus neuraminidase are shaped by immune history

2025-09-04

Abstract excerpt

H5N1 highly pathogenic avian influenza viruses have spread globally and pose a risk for a human pandemic. Prior studies suggest that early life exposures to group 1 influenza viruses (H1N1 and H2N2) prime antibodies that cross-react to the hemagglutinin of H5N1, which is also a group 1 virus. Less is known about how immune history affects antibody responses against the neuraminidase (NA) of H5N1 viruses. Here, we...

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Literature Corpus work: 4f2f9bc9-fcfa-5f07-8e8c-139aff449124
DOI: 10.1101/2025.09.02.25334929

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